Human GPC3 / Glypican-3, His Tag

货号：PHA134    表达系统：HEK293

Human GPC3 / Glypican-3(S495A, S509A), Fc Tag

货号：PHD650    表达系统：HEK293

A： Immobilized Human GPC3 / Glypican-3, His Tag at 2 μg/mL can bind Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab), EC50=0.003621μg/mL.

B：Immobilized Human GPC3 / Glypican-3(S495A, S509A), Fc Tag at 2 μg/mL can bind Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab), EC50=0.05101 μg/mL.

A： Huh-7 cells were stained with anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS.

B：HEP3B cells were stained with anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS.

A：The endocytosis ratio codrituzumab by HuH-7 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 40%at antibody concentration of 1 nM.

B：Anti-GPC3 / Glypican-3 Reference Antibody (Codrituzumab) induced ADCC activity was evaluated using human GPC3 CHOS Cell. The max Lysis rate was approximately 30%.

Human GPC3 / Glypican-3 CHO Cell Line（Monoclonal）

货号：XHB597    宿主细胞：CHO

Human GPC3 / Glypican-3 HEK293 Cell Line（Monoclonal）

货号：XHB598    宿主细胞：HEK293

A：Human GPC3 / Glypican-3 CHO Cell Line were stained with Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS.

B：Human GPC3 / Glypican-3 HEK293 Cell Line were stained with Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS.